28 games
| Date | Opponent | Result |
|---|---|---|
| 2000-11-27 | @ Oldham County () | L 48-69 |
| 2000-12-04 | v Central Hardin () | L 44-51 |
| 2000-12-07 | @ Floyd Central, IN () | L 47-63 |
| 2000-12-08 | v North Bullitt () | W 42-28 |
| 2000-12-12 | @ Elizabethtown () | W 51-38 |
| 2000-12-15 | @ Bullitt Central () | L 40-46 |
| 2000-12-20 | v Bardstown () | W 56-50 |
| 2000-12-27 |
vs Paducah Tilghman
() Lady Panther Invitational |
W 78-42 |
| 2000-12-28 |
vs North Laurel
() Lady Panther Invitational; overtime |
W 59-57 |
| 2001-01-02 |
@ Daviess County
() Lady Panther Invitational championship |
L 46-54 |
| 2001-01-09 | v North Hardin () | L 41-44 |
| 2001-01-11 | v Breckinridge County () | W 48-33 |
| 2001-01-13 | v Bullitt East () | W 65-43 |
| 2001-01-15 | @ Grayson County () | W 50-41 |
| 2001-01-18 | v Elizabethtown () | L 38-57 |
| 2001-01-23 | @ Hancock County () | W 59-32 |
| 2001-01-25 | v LaRue County () | W 45-24 |
| 2001-01-30 | @ Central Hardin () | L 40-54 |
| 2001-02-02 | v Fort Knox () | W 60-50 |
| 2001-02-06 | @ North Hardin () | L 41-42 |
| 2001-02-09 | v Nelson County () | W 51-37 |
| 2001-02-13 | @ Fort Knox () | L 41-59 |
| 2001-02-15 | @ Fern Creek () | W 51-39 |
| 2001-02-23 | @ Southern () | W 67-37 |
| 2001-02-27 |
vs North Hardin
() 17th District Tournament |
W 41-38 |
| 2001-03-01 |
vs Central Hardin
() 17th District Tournament |
W 56-50 |
| 2001-03-03 |
vs Elizabethtown
() 17th District Tournament championship |
L 46-59 |
| 2001-03-08 |
vs Hart County
() 5th Region Tournament |
L 38-56 |